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The role of gene alterations resulting from childhood adversity in adults addicted to heroin and a search for blood tests to predict addiction vulnerability are part of sweeping research that scientists are launching at the University of California, Irvine.

Dr. Shahrdad Lotfipour, shares his story of why he became an addiction scientist, how he did it, and what his laboratory is working on now. Through a journey of personal…

Associate Professor Christie Fowler discusses potential biases in experimentation and data interpretation in a new podcast from the Society for Neuroscience’s Foundations of Rigorous Neuroscience Research program. Hear how Professor Fowler and other neuroscientists minimize bias in their research!

In his new study, Professor Mahler and his team utilized a translationally-relevant rat model to investigate THC effects in adolescents of both sexes. They conducted a systematic investigation of THC metabolism and distribution in the brain and blood, and characterized its effects on behavior and activity of brain reward and stress neural networks.

The UC Irvine Center for Addiction Neuroscience (ICAN) was established to bring together addiction research faculty from across UCI for the first time, to identify areas of collaboration to leverage for highly competitive research funding opportunities. In addition to advancing the national and international footprint of UCI’s substance abuse and dependence research, ICAN seeks to: enhance the education of students (undergraduate and graduate) and postdoctoral trainees in the field of addiction research, increase public awareness on matters of addiction through specialized outreach programs, develop patient care/outreach initiatives, and attract additional philanthropic support to enhance research discoveries at UCI.